Brewer Creek, on the south side of the river between Limehouse Cove and Glebe Bay, contains within it Pocahontas Creek, an area that from older maps looks basically to have been an occluded tidal pond. Brewer Creek itself was named after John Brewer (or his descendants), a prominent property owner in the area who was given a 400-acre land grant by Cecilius Calvert (the 2nd Lord Baltimore) in 1651 (below).
The land grant is below:
John Brewer 400 acres Cecelius Absolute Lord and Proprietor of the Province of Maryland and Avalon Lord Baron of Baltimore.
To all persons to whom these presents shall come Greetings in Our Lord God everlasting.
Know Ye that we for in consideration that John Brewer of this Province, planter hath due unto him Four Hundred Acres of the land and upon such conditions and terms as are explained in our conditions of said Plantations of our Said Province of Maryland under our Greatest Seal at Arms, bearing date at London, the second day of July in the year of our Lord God 1649, it remaining upon Record in our Said Province of Maryland with such alterations as in them are made by our Declaration bearing date Sixth and Twentieth day of August, Anno Domini 1651, likewise remaining upon record in our Said Province of Maryland, do hereby grant to the said John Brewer a parcel of land called Brewerton lying on the West Side of the Chesapeake Bay and on the West Side of a River in the said Bay called Rhode River next adjoining the land of Thomas Besson the elder.
Beginning at the said Besson's Northern most boundary, there is a Poke Hickory Tree, Bounding on the East by a line drawn North and by West from the said Poke Hickory for breadth Two Hundred Perches to a marked Oak; on the North by a line drawn West and by South from the said Oak for length Three Hundred and Twenty Perches on the West, by a line drawn South and by East thereon of the West and by South line for breadth, Two Hundred Perches until it intersects Parallel drawn from the land of the said Besson on the South, with said land and parallel, containing and now laid out Four Hundred Acres more or less, together with all profits, rights and benefits thereunto belonging, Royal minus excepted to have and to hold the same unto him, the said John Brewer his heirs and assigns forever, to be holden of us and our heirs as of our Manor of Baltimore in free and common Socage by fealty only for all services yielding and paying therefor yearly unto us and our heirs at our receipt at St Mary's at the two most usual Feasts in the year viz: at the Feast of the Annunciation of the Blessed Virgin Mary, and at the Feast of St Michael the Archangel by even and equal portions of rent of Eight Shillings Sterling in Silver or Gold or the full value thereof in such commodities as we or our heirs of such officer or officers appointed by us or our heirs from time to time to collect and receive the same shall accept in discharge thereof at the choice of us and our heirs of such officer or officers as aforesaid. Given at St Mary's under our Great Seal of our Said Province of Maryland, Anno Domini 1651. Witness our Trusty and well beloved Josias Tendall Esq., our Lieutenant of our Said Province.
Brewer Creek was formerly named Pyther's Creek after William Pyther. It is also formerly described as Bessons Creek (presumably after Thomas Besson) in Amrhein, John L. Jr. "The Middle And Upper Bay of Chesapeake as it appeared Circa 1690 with all the Rivers, Shoals, Channels, Islands, Entrances, Soundings and Sailing Marks." Salisbury, Maryland: Ryan and Black, 1987.